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沱江流域饮用水源地抗生素污染的时空变化、生态风险及人体暴露评估

王若男 何吉明 向秋实 熊杰 刘强 胥倩 任朝辉

王若男, 何吉明, 向秋实, 熊杰, 刘强, 胥倩, 任朝辉. 沱江流域饮用水源地抗生素污染的时空变化、生态风险及人体暴露评估[J]. 环境科学研究, 2022, 35(10): 2404-2412. doi: 10.13198/j.issn.1001-6929.2022.07.11
引用本文: 王若男, 何吉明, 向秋实, 熊杰, 刘强, 胥倩, 任朝辉. 沱江流域饮用水源地抗生素污染的时空变化、生态风险及人体暴露评估[J]. 环境科学研究, 2022, 35(10): 2404-2412. doi: 10.13198/j.issn.1001-6929.2022.07.11
WANG Ruonan, HE Jiming, XIANG Qiushi, XIONG Jie, LIU Qiang, XU Qian, REN Zhaohui. Spatial and Temporal Distribution, Ecological Risk and Human Exposure Assessment of Antibiotics in Drinking Water Sources in Tuojiang River Basin[J]. Research of Environmental Sciences, 2022, 35(10): 2404-2412. doi: 10.13198/j.issn.1001-6929.2022.07.11
Citation: WANG Ruonan, HE Jiming, XIANG Qiushi, XIONG Jie, LIU Qiang, XU Qian, REN Zhaohui. Spatial and Temporal Distribution, Ecological Risk and Human Exposure Assessment of Antibiotics in Drinking Water Sources in Tuojiang River Basin[J]. Research of Environmental Sciences, 2022, 35(10): 2404-2412. doi: 10.13198/j.issn.1001-6929.2022.07.11

沱江流域饮用水源地抗生素污染的时空变化、生态风险及人体暴露评估

doi: 10.13198/j.issn.1001-6929.2022.07.11
基金项目: 四川省环境保护科技项目(No.2019HB04)
详细信息
    作者简介:

    王若男(1987-),女,江苏徐州人,高级工程师,硕士,主要从事环境监测分析研究,441546756@qq.com

    通讯作者:

    任朝辉(1968-),女,四川成都人,高级工程师,硕士,主要从事环境监测研究,630339657@qq.com

  • 中图分类号: X83

Spatial and Temporal Distribution, Ecological Risk and Human Exposure Assessment of Antibiotics in Drinking Water Sources in Tuojiang River Basin

Funds: Project for Environmental Protection Technology of Sichuan Province, China (No.2019HB04)
  • 摘要: 为探讨抗生素在饮用水源地的分布现状,采用固相萃取-高效液相色谱质谱联用法对四川省沱江流域典型城市饮用水源地中35种抗生素进行了测定,并计算了风险商(RQ)及人体通过饮用水暴露于抗生素的量. 结果表明:① 沱江流域饮用水源地35种抗生素被广泛检出,在春季、夏季、秋季、冬季的浓度分别为n.d.(低于检出限)~114.696、n.d.~536.322、n.d.~69.488和n.d.~90.461 ng/L,检出率分别为0~85.7%、0~92.9%、0~100.0%和14.3%~100.0%. ② 抗生素在冬季检出率最高,达74.3%,喹诺酮类在各季节的平均浓度呈冬季≈夏季>春季>秋季的特征,四环素类在秋季浓度最低,其余5类抗生素未发现显著的时间变化. ③ 磺胺类和大环内酯类存在一定的空间分布特征,而其余抗生素未呈现显著空间分布差异. ④ 磺胺嘧啶在春季、秋季和冬季以及盐酸金霉素在夏季对生态系统有较高的生态风险. 氧氟沙星和盐酸四环素在春季、夏季和冬季的风险商介于0.10~1.00之间,在相应季节对沱江流域可能造成中等生态风险. ⑤ 短期内居民通过饮用沱江流域饮用水源地水暴露于抗生素的风险可以忽略不计,但长期低剂量暴露带来的健康风险问题有待进一步研究. 研究显示:抗生素污染广泛存在于沱江流域饮用水源水中,其中以兽用抗生素为主,表明农业活动可能对该流域抗生素污染贡献较大;沱江流域饮用水源地水中抗生素总体处于中低生态风险,基于该研究数据沱江流域内人群饮用水源水暴露于抗生素的量较低,相对安全.

     

  • 图  1  沱江流域饮用水源地采样点分布

    Figure  1.  Sampling sites distribution of drinking water sources in the Tuojiang River Basin

    图  2  沱江流域饮用水源地不同季节抗生素浓度分布

    Figure  2.  Seasonal variation of the investigated antibiotics in drinking water sources from Tuojiang River Basin

    图  3  沱江流域饮用水源地抗生素污染的生态风险

    Figure  3.  Ecological risk of antibiotics in drinking water sources in the Tuojiang River Basin

    表  1  沱江流域饮用水源地不同季节抗生素浓度

    Table  1.   Concentration of antibiotics in drinking water sources of the Tuojiang River Basin in different seasons ng/L

    类别 单体 春季 夏季 秋季 冬季
    平均值 最小值 最大值 平均值 最小值 最大值 平均值 最小值 最大值 平均值 最小值 最大值
    喹诺酮类 ENOXA 0.309 n.d. 2.279 2.317 n.d. 16.082 n.d. n.d. n.d. 0.831 0.101 3.358
    ENROF 0.050 n.d. 0.368 0.260 n.d. 1.585 n.d. n.d. n.d. 0.296 n.d. 0.706
    LEVOF 0.289 n.d. 1.708 1.685 n.d. 16.244 0.022 n.d. 0.271 2.802 0.316 22.744
    NORFL 0.288 n.d. 1.515 0.878 n.d. 4.238 0.091 n.d. 0.791 0.870 n.d. 5.714
    CIPHY 0.237 n.d. 1.144 1.479 n.d. 7.246 0.308 n.d. 4.235 0.708 n.d. 3.487
    DANME 0.160 n.d. 0.983 10.737 n.d. 40.108 0.265 n.d. 3.568 2.071 n.d. 7.844
    LOMHY 0.032 n.d. 0.106 0.110 n.d. 0.682 0.027 n.d. 0.202 0.241 n.d. 0.569
    OFLOX 0.670 n.d. 5.259 0.691 n.d. 7.885 0.034 n.d. 0.403 2.719 0.173 23.835
    β-内酰胺类 PENGO 6.776 n.d. 65.056 146.503 n.d. 536.322 5.638 n.d. 35.876 2.077 n.d. 6.095
    AMOTR 4.600 n.d. 14.498 n.d. n.d. n.d. n.d. n.d. n.d. 8.693 n.d. 49.498
    AMPTR 1.456 n.d. 3.609 28.025 n.d. 66.975 n.d. n.d. n.d. 2.640 n.d. 6.481
    大环内酯类 RIFAM 0.874 n.d. 11.357 n.d. n.d. n.d. n.d. n.d. n.d. 0.335 n.d. 1.262
    ROXIT 1.198 n.d. 11.507 3.793 n.d. 26.371 0.945 0.466 2.060 1.922 n.d. 7.045
    ERYTH 8.317 n.d. 114.696 0.809 n.d. 5.830 0.145 n.d. 1.044 0.050 n.d. 0.204
    AZIDI 0.147 n.d. 1.257 n.d. n.d. n.d. 0.484 n.d. 2.592 0.497 n.d. 2.555
    TYLTA n.d. n.d. n.d. n.d. n.d. n.d. n.d. n.d. n.d. 0.077 n.d. 0.873
    磺胺类 SCHLO 0.419 n.d. 1.923 n.d. n.d. n.d. 0.352 n.d. 2.784 0.733 n.d. 3.088
    SDIAZ 0.272 n.d. 1.669 n.d. n.d. n.d. 0.307 n.d. 1.142 0.506 0.065 2.250
    SDIME 0.193 n.d. 0.974 1.208 n.d. 4.486 0.656 n.d. 1.358 0.206 n.d. 0.610
    SMERA 0.457 n.d. 1.592 0.141 n.d. 1.619 0.117 n.d. 0.888 0.197 n.d. 0.761
    SMETA 0.427 n.d. 2.520 0.247 n.d. 1.916 5.198 n.d. 69.488 0.416 n.d. 1.504
    SMETO 2.024 n.d. 12.732 1.321 n.d. 7.349 0.815 n.d. 3.711 2.796 0.142 11.072
    SPYRI 0.331 n.d. 1.181 n.d. n.d. n.d. 0.569 n.d. 2.562 0.183 n.d. 0.563
    STHIA 0.368 n.d. 0.910 0.145 n.d. 0.944 0.798 n.d. 3.738 0.279 n.d. 1.350
    TRIME 0.942 n.d. 3.844 0.645 n.d. 4.001 6.342 n.d. 29.317 2.488 n.d. 10.196
    四环素类 CHLHY 1.779 n.d. 6.912 8.510 n.d. 26.980 n.d. n.d. n.d. 0.933 n.d. 3.657
    DEMHY 3.544 n.d. 16.289 7.349 n.d. 40.527 0.347 n.d. 4.411 0.410 n.d. 2.080
    TETHY 1.985 n.d. 8.686 4.704 n.d. 18.740 0.143 n.d. 1.867 0.728 n.d. 3.403
    OXYHY 0.668 n.d. 4.635 1.825 n.d. 20.417 0.522 n.d. 2.547 0.575 n.d. 3.396
    硝基咪唑类 RONID 3.401 n.d. 42.840 n.d. n.d. n.d. 1.339 n.d. 7.184 0.797 n.d. 2.669
    METRO 0.086 n.d. 0.416 0.418 n.d. 1.056 1.972 n.d. 11.347 2.786 0.133 11.943
    DIMET 1.875 n.d. 13.006 4.235 n.d. 16.415 2.686 n.d. 7.409 9.052 0.252 27.401
    酰胺醇类 CHLOR 15.315 n.d. 51.337 n.d. n.d. n.d. 0.033 n.d. 0.261 1.202 n.d. 3.269
    FLORF 5.815 n.d. 30.410 n.d. n.d. n.d. 0.155 n.d. 1.429 13.114 0.158 90.461
    THIAM 3.008 n.d. 17.982 n.d. n.d. n.d. 0.050 n.d. 0.212 0.909 n.d. 3.526
    注n.d.表示低于检出限.
    下载: 导出CSV
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  • 收稿日期:  2022-01-17
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