2020年我国大气臭氧对慢性阻塞性肺病死亡影响的疾病负担分析和健康经济学评价
COPD Mortality Burden and Related Health Economic Assessment Associated with Ambient Ozone in 2020 in China
-
摘要: 大气臭氧暴露对人群慢性阻塞性肺病(chronic obstructive pulmonary disease, COPD)的影响不断加剧。为评价大气臭氧暴露对COPD的不良影响,量化与大气臭氧暴露相关的COPD 死亡负担和相应的健康经济损失,收集2020年中国大陆31个省、自治区、直辖市的峰季大气臭氧浓度数据、社会经济及人口数据,基于一项系统综述和荟萃分析研究中确立的大气臭氧暴露与COPD死亡的暴露-反应关系,以世界卫生组织2021年提出的峰季臭氧环境质量指导浓度限值60 µg/m3为参考,分别估算中国大气臭氧暴露的COPD归因死亡人数和经济损失。结果表明: ①2020年中国大气臭氧暴露的COPD总死亡风险比为1.12 (95%CI:1.00 — 1.21)。②2020年中国归因于大气臭氧暴露的COPD死亡人数为10.12 (95%CI:0.00 — 17.49)万。 ③2020年中国大气臭氧暴露造成的COPD的健康经济损失为 2131亿元,占GDP的0.21%。研究显示,2020年中国大气臭氧暴露造成了较大的COPD疾病负担和经济损失,在气候变化和控制碳排放战略实施背景下,为达到世界卫生组织2021年提出的峰季臭氧环境质量指导浓度限值60 µg/m3的目标,中国仍需要因地制宜制定相关政策降低臭氧浓度,积极应对大气臭氧暴露对人群健康的危害。Abstract: The harmful effects of ambient ozone exposure on chronic obstructive pulmonary disease (COPD) mortality are increasing. To evaluate the effects of COPD mortality burden and the corresponding economic losses associated with ambient ozone exposure, the peak-season ambient ozone concentration data and mortality records of 31 provinces, autonomous regions and municipalities in mainland China in 2020 were collected. Based on the hazard ration between COPD deaths and ambient ozone exposure cited from a study of systematic review and meta-analysis, risk of COPD deaths attributed to ozone exposure was estimated with reference to the Air Quality Guidelines level of peak season (60 µg/m3) proposed by the World Health Organization in 2021. Besides, socioeconomic, and demographic data were collected to quantify the attributable deaths and corresponding economic losses due to ambient ozone exposure in 31 provinces, autonomous regions and municipalities of China. The results showed that the exposure-response hazard ratio between ambient ozone and COPD mortality is 1.12 (95%CI:1.00 — 1.21) per 10 μg/m3, with increased COPD mortality risk for ambient ozone. As estimated, 101.15 (95%CI:0.00 — 174.89)thousands COPD deaths are attributable to ambient ozone in 2020 in China. The corresponding economic losses is 213.14 billion yuan. The proportion of the overall economic loss to the gross domestic product (GDP) is accounting for 0.21% of GDP. The study indicated that ambient ozone exposure has led to substantial COPD mortality and economic loss in China. It is necessary to formulate corresponding policies to reduce ozone concentration in accordance with local conditions to achieve the target of the peak season ozone environmental quality guideline limit of 60 µg/m3 proposed by the World Health Organization in 2021, and actively respond to the health threats of ambient ozone exposure to human.
点击查看大图
计量
- 文章访问数: 113
- HTML全文浏览量: 15
- PDF下载量: 30
- 被引次数: 0