Industrial parks, as specific areas with a concentration of production-oriented enterprises, generate significant amounts of industrial solid waste (ISW) during the production process, posing challenges to the environment and sustainable development. Improper handling of ISW leads to environmental impacts and resource wastage, hindering the progress of green development and transformation in the region. To address these issues, effective waste management solutions are essential in industrial parks. The synergistic utilization of ISW plays a crucial role in enhancing waste management efficiency and promoting sustainable development, maximizing economic benefits while minimizing environmental impacts. Through a multidimensional evaluation of common ISW comprehensive utilization technologies in industrial parks and the application of the Analytic Hierarchy Process, the most suitable combination of ISW synergistic utilization technologies can be identified. Baotou Aluminum Industrial Park was taken as a representative case and finds that schemes involving large-scale utilization of solid waste, multi-level utilization of aluminum ash, and synergistic utilization of major overhaul slag and carbon slag are most suitable for ISW synergistic utilization in this industrial park. These solutions effectively address the existing issues of ISW in the park and contribute to the ecological protection and high-quality development in the Yellow River Basin. This research provides scientifically sound decisions and proposals for solid waste management in industrial parks, offering valuable references for green development and resource circularity. By enhancing the synergistic utilization capability and overall economic value of solid waste, this case also serves as a reference and inspiration for other resource-based cities and industrial parks seeking sustainable solutions.