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城市河流中WWMPs的迁移转化试验研究
周海东,王瑾雅丹
作者单位E-mail
周海东 上海理工大学 zhouhaidong@usst.edu.cn 
王瑾雅丹 上海理工大学  
摘要:
以城市河流中的13种典型污水印记药物(WWMPs)为目标物,采用固相萃取技术与超声溶剂萃取+固相萃取技术分别对水相和沉积相进行富集浓缩,以及 UHPLC-HESI-MS/MS检测的方法,通过静态摇瓶试验研究分析了目标物在城市河流中主要的迁移转化机理。结果表明,城市河流中阿奇霉素、克拉霉素、阿替洛尔的降解主要是生物降解作用,降解率可达90%以上。沉积物对卡马西平的吸附作用明显,但是难以被水解和生物降解,而且其吸附和解吸是一个相对平衡的过程,导致卡马西平能够稳定存在。4种亲水性化合物不易被沉积物吸附,其余9种属疏水性化合物,吸附能力取决于其辛醇-水分配系数。此外,光降解试验表明了在实际环境中,很多目标物受颗粒物和光敏剂的影响,不易发生直接光降解。
关键词:  静态摇瓶试验  吸附  光降解  生物降解  沉积相
DOI:
分类号:
基金项目:国家自然科学基金项目(面上项目,重点项目,重大项目)
Experimental studies on transfer and transformation of Wastewater-marking pharmaceuticals in urban rivers
zhouhaidong,wangjinyadan
Abstract:
13 typical WWMPs with high detected frequencies in urban rivers were selected as the target compounds. Solid phase extraction (SPE) and ultrasonic solvent extraction combined with SPE were used for enrichment and congcentration of the target pharmaceuticals from water and sediment samples, respectively. Then, the simultaneous detection of multi-target WWMPs and their metabolites were established through ultra high-performance liquid chromatography combined with tandem mass spectrometry system (UHPLC-MS/MS).Based on the detection, the transport-transformation mechanism (adsorption, biodegradation, photodegradation) of target WWMPs were investigated through static shake-flask experiments. The results showed that the main degradation pathway of azithromycin, clarithromycin and atenolol was biodegradation in urban rivers, and the removal rates were above 90%. Although carbamazepine (CBM) showed moderate adsorption affinity in the sediment, it was recalcitrant to hydrolysis and biodegradation, and its concentration was stable in the water phase because of adsorption-desorption equilibrium. In the adsorption experiments, 4 hydrophilic compounds were hard to be adsorbed on sediment while the other 9 hydrophobic compounds ‘adsorption affinity was mainly depended on its octanol-water partitioning coefficient (Kow). Also, the photodegradation experiment indicated that in the actual environments, many target WWMPs are impacted by suspended particulates and photosensitizer so that direct photodegradation is not easy to happen.
Key words:  static flask-shaking test  adsorption  photodegradation  biodegradation  sediment