Abstract: In recent years, with the continuous increase in the number of vehicles, air pollution and health effects caused by vehicle pollution have been increasing. The demand for controlling the interior air quality in vehicles is continuously increasing, and interior air quality issues in vehicles have been receiving widespread attention from the public. This article focuses on vehicle interior air quality control and combs and analyzes the current domestic and international standards for controlling interior air quality in vehicles, as well as the quality control standards for pollutants of vehicle interior materials in China. Moreover, the sampling methods for semi-volatile organic compounds in vehicle interior air and the key substances were also summarized and analyzed. The results show the following: ① Volatile organic compounds are the key indicators of current vehicle interior air quality control standards in various countries, and the limit values vary. Except for Japan, semi-volatile organic compounds have not yet been included in the control standards. ② In China, organic compounds account for 66.90% of all quality control indicators for vehicle interior material quality control standards, of which these organic compound indicators, semi-volatile organic compounds account for 30.94%. The semi-volatile organic compounds in these quality control standards are mostly plasticizers and flame retardants that pose health risks to humans. ③ Studies of semi-volatile organic compounds in vehicle interior air involve gas-phase, particle-phase, and dust samples. More than 66.67% of the samples were collected using active sampling methods. Flame retardants and plasticizer substances, such as brominated flame retardants, phosphorus-based flame retardants, phthalates, and perfluoro compounds, are the focus of these studies, accounting for 88.14% of the overall research. Accordingly, two suggestions are provided for the management of vehicle interior air quality to further improve its management in China and reduce the health hazards it causes. First, based on the existing vehicle interior air quality management standards and technical guidelines, the government needs to appropriately expand the scope of quality control indicators and add semi-volatile organic compounds, such as flame retardants and plasticizers. Second, it is necessary to improve the technical guidelines for collecting air quality samples inside vehicles and to formulate standard operating procedures for sampling semi-volatile organic compounds.