基于生物可给性的华南某农用地土壤重金属复合污染非致癌健康风险评估
Non-carcinogenic health risk assessment of heavy metals combined exposure to soil of an agricultural land in Southern China based on bioavailability
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摘要: 摘要 : 重金属对人体多种靶器官存在健康风险,同时重金属之间的相互作用也会对其累积的效果产生影响,但是传统健康风险评价模型并未考虑这两种因素的影响,不能反映重金属对人体的真实风险情况。为评估华南某典型重金属污染农用地土壤重金属暴露对儿童的非致癌健康风险,对土壤中As、Cd、Cr、Cu、Pb、Ni、Zn、Hg进行检测,采用单项污染指数法 (Pi) 及内梅罗综合污染指数法 (Pc) 评价其污染程度,并引入重金属生物可给性和BINWOE法对其非致癌健康风险进行修正。结果表明:研究区土壤中单一重金属的危害指数值 (HIHRA) 小于1,非致癌健康风险处于可接受水平,其中95分位土壤中多种重金属叠加风险 (HIHRA) 大于1,多种重金属复合污染存在非致癌健康风险。进一步采用BINWOE法对四种重金属(As、Cd、Cr、Pb)的复合非致癌健康风险进行评估,四种金属对靶器官总的非致癌健康风险指数HIWOE为1.8143,是传统非致癌健康风险(1.3440)的1.35倍,非致癌健康风险经重金属生物可给性修正后为1.2348,仍处于不可接受水平。因此,在对重金属进行非致癌健康风险评价时,考虑各重金属的靶器官和重金属间在靶器官中的相互作用是重要的。Abstract: Abstract: Heavy metals could lead to adverse health risks for multiple target organs of humans, and their interactions may affect the cumulative effects of heavy metals. However, the traditional health risk assessment models did not take the influences of these two factors into account, and failed to reflect the accurate risk of heavy metals to the human body. In order to evaluate the non-carcinogenic health risk of the children exposed to heavy metals from a typical agricultural land in Southern China, levels of As, Cd, Cr, Cu, Pb, Ni, Zn and Hg in soil were detected and their pollution degrees were evaluated by single factor pollution index method (Pi) and Nemerow comprehensive pollution index method (Pc). In this study, the bioavailability of heavy metals and the BINWOE method were employed to optimize the non-carcinogenic health risk models. The results showed that the non-carcinogenic health risk index (HIHRA) of every single metal was less than 1, and thus their non-carcinogenic health risks were all at acceptable levels. However, the superimposed health risk index of heavy metals (HIHRA) in the 95th quartile was greater than 1, indicating that the non-carcinogenic health risk exist of combined pollution form the multiple heavy metals. BINWOE method was used to assess the composite non-carcinogenic health risk of four heavy metals (As, Cd, Cr, Pb). The total non-carcinogenic health risk index (HIWOE) of the four metals to target organs was 1.8143, which was 1.35 times of the traditional HIHRA (1.3440). Furthermore, the non-carcinogenic health risk was 1.2348 by modifications of heavy metal bioavailability, which was still at an unacceptable level. Therefore, our results emphasize the considering the target organs of each heavy metal as well as their interaction in the target organs for assessing the non-carcinogenic health risk of multiple heavy metals.
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Key words:
- agricultural land /
- heavy metal /
- soil /
- non-carcinogenic health risk /
- target-organ toxicity
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