Abstract: The effects of sulfate reduction of the anaerobic treatment of sulfate wastewater were studied by the operation of a series of daily feed digesters.The experimental results showed,at temperature of 35℃ and pH 7.2-7.4,when the feed ratio of COD to sulfate was more than 10,the sulfate reduction had no significant inhibition of methanogenesis.When the feed ratio COD to sulfate was less than 5 and the COD loading rate was nore than 2.05kgCOD / m3·d,the reactor would be seriously inhibited When the feef ratio of COD to sulfate was less than 2,the COD loading rate receivable to reactor couldn’t be more than 1.05kgCOD / m3·d.The smaller the ratio of COD to sulfate,the lower the COD loading rate receivable to anaerobic reactor.The high sludge concentration in the reactor is beneficialto the treat ment of sulfate wastewater.