Abstract: Lipid yields in aerosols from five major cities and districts of the Pearl River Delta were from 1.50 to 61.04 μg/m³.Those from Guangzhou in autumn were highest (36.85 μg/m³ in average), those from Macao comes second; in spring lipid yields from Hongkong were lower than that from Guangzhou; and in summer lipid yields from Shenzhen were higher than that from Guangzhou; in winter lipid yields from Zhuhai were lowest. More than 80 polycyclic aromatic hydrocarbons (PAH) were identified and analyzed; the concentration of preceding controlled PAH were from 1.32 to 228.56 ng/m³; their distribution pattern was similar to that of lipid yields except Macao and Hongkong with lower concentration (9.02~40.52 ng/m³ and 0.68~14.88 ng/m³, respectively). Organic pollution mainly originated from vehicle exhaust in this area is more serious than that in some foreign cities. The most important wayto control the organic pollution is to have vehicles equipped with catalytic purifiers and to make relevant regulations.