Abstract: Soil pollution has become one of the hinder factors of urban land sustainable development during city urbanization, while organic pollutants have beenmore important soil pollutants. Under the background of the lack of environmental quality standard at present in China, an urban land functional replacement site was used as a case to analyze and assess quantitatively the potential hazard to future residents brought by soil organic pollutants during land replacement, adopting the method of healthy severity assessment. It was identified that soil environment of this area was mainly polluted by 2,4-dinitrophenolate, the pentachlorophenol as well as PAHs. Due to other organic pollutants not included in calculation, the results of health influence drawn in this study are less than the actual environmental pollution degree. With the development of environmental management, the Health Risk Assessment (HRA) should be strengthened during urban land functional replacement.