Abstract: Nine pooled samples, belonging to two food categories (fish and duck),were collected in 2006 from coastal waters of Qingdao and Chongming Island of Shanghai. Concentrations of co-planar polychlorinated biphenyls (co-PCBs) and polychlorinated naphthalenes (PCNs) were measured by HRGC-HRMS, and potential health risks for consumption of fish and duck were preliminarily discussed. In fish, the mean concentrations of co-PCBs and PCNs respectively were about 4，041 and 225 pg/glipid from Qingdao, and 3，318 and 640 pg/g lipid from Chongming Island; in duckmeat, the mean concentrations were about 966 and 43.8 pg/g lipid, respectively. The homologue profiles of PCNs in fish from Qingdao and Chongming Island were quite different. The total co-PCB-TEQ (toxicity equivalence) and PCN-TEQ ranged from 0.68 to 11.40 pg(WHO-TEQ)/g lipid and from 0.001 to 0.210 pg(WHO-TEQ)/g lipid for fish and duck meat, respectively. Based on the food consumption patterns of the local populations, the average daily intake of dioxin-like compounds from the consumption of fish and duck was estimated to be less than the tolerable daily intake (TDI), 1-4 pg(WHO-TEQ)/kg body weight, suggesting low health risk for the local populations.