Abstract: Samples of cage cultured carp (Cyprinus carpio) in different growth periods were collected in the East Dongting area from February to July 2012. The w(Pb), w(Zn), w(Cd), w(Cu) were measured by the atomic absorption spectrophotometry in water samples, fodders and the gills, livers and muscles of carp. The results showed that the water quality belonged to level Ⅰ according to the “Environmental Quality Standards for Surface Water” (GB 3838-2002). The mass fraction of heavy metals in the fodder was relatively higher, which made the fodder become the main possible source of heavy metals pollution in carp. The w(Pb) and w(Cu) increased with the fish growth. In the gills, Pb were not detected (nd) while the w(Cu) were 0.143-0.703mg/kg. In the livers, w(Pb) and w(Cu) ranged in 0.006-0.181mg/kg and in 0.625-6.177mg/kg respectively. In the muscles, w(Pb) and w(Cu) were nd-0.034mg/kg, nd-0.161mg/kg respectively. During the growth of the carp, the w(Zn) and w(Cd) increased firstly and decreased later. During the first to the 4^th month, the w(Zn) in gills, livers and muscles increased from 40.121,1.302,2.032mg/kg to 258.964,6.155,8.011mg/kg respectively. Similarly, the w(Cd) increased from 0.015,0.031,0.003mg/kg to 0.078,0.151,0.021mg/kg respectively in gills, livers and muscles. After four months, the w(Zn) in gills, livers and muscles declined gradually to 173.182,4.219,5.490mg/kg respectively while the w(Cd) declined to 0.037,0.111,0.018mg/kg at the same time. During the whole growth process of the fish, the liver was the main enrichment site for Pb, Cd and Cu while the gills were the main enrichment site for Zn. The mass fraction of heavy metals in muscles was the lowest among all tissues. All these three parts strongly correlated.