Abstract: As an advanced oxidation technology, catalytic wet oxidation (CWAO) method has been developed in recent few decades for treating non-biochemical organic wastewater. It is a chemical process with a high temperature (125-320℃) and high pressure (0.5-20.0MPa) under the conditions of oxygen or air as oxidant. The organic pollutants decompose onto inorganic or organic small molecules, such as carbon dioxide and water. The catalyst preparation is the key step for CWAO, and the composite multicomponent load type catalysts of transition metal and rare-earth metal were studied in this paper. The methyl orange analog dyeing wastewater was treated with the CWAO method. The catalysts were prepared with an excessive impregnation method. The catalyst activity was evaluated with the COD_Cr removal rates and decolorization removal rates, while the catalyst stability was evaluated with the concentrations of metal ions dissolved in the treated wastewater. The results showed that the compositions of multicomponent metal catalysts were Cu, Fe, La, and the composition ratio was m(Cu)∶m(Fe)∶m(La)=1∶1∶2, and the dipping conditions are at 35℃, for 8h at dynamic and common impregnation, and the calcination conditions are at 450℃, for 3h. Using the catalyst of Cu-Fe-La/FSC, the simulated dyeing and printing wastewater was treated by the CWAO method, and the COD_Cr removal rate and the decolorization rate of wastewater reached 79.1% and 98.9% respectively, this indicated that the activity of catalyst is higher; After the catalyst is used in the wastewater treated, the dissolution concentrations of metal element Cu, Fe, La, Al are 6.1,2.4,2.2,3.2mg/L, so the dissolution concentrations of the metal elements are low, so the stability of the catalysts is higher. This study provides a scientific basis to develop the rare-earth composite catalysts for the printing and dyeing wastewater treating in the CWAO process.