Abstract: A batch incubation experiment was conducted to analyze the influences of covering particle diameter, ammonia nitrogen, nitrate nitrogen, zinc (Zn) and chrome (Ⅵ) on CH₄ oxidation potentials (MOPs) of cover sandy soil (CSS) and uncovered sandy soil (USS) in landfills. The results indicated that a suitable soil particle diameter was able to promote MOPs of CSS and USS to a certain extent (P＜0.05). The optimum soil particle diameter appeared when particle diameters of CSS and USS were between 1.00 and 2.00 mm, in which the MOPs of CSS and USS were 0.24 and 0.12 μmol/(g·h), respectively. Moreover, low-concentration ammonia nitrogen and nitrate nitrogen promoted MOPs of CSS and USS, while the high-concentration ones inhibited MOP significantly. The experiment demonstrated that the critical concentration of ammonia nitrogen and nitrate nitrogen added to CSS and USS was 200 mg/kg. Meanwhile, CSS adapted to concentration fluctuation more flexibly than USS. The experiment revealed that inhibitory effects of Zn and Cr(Ⅵ) on CSS and USS were in direct proportion to the concentrations of the heavy metals. Zn exerted stronger inhibitory effect on MOP of CSS than Cr did, and the degree of the inhibitory effects on MOP of USS was explicitly much more intense than those on CSS. Therefore, the proper soil particle diameter and low contents of inorganic nitrogen and heavy metals are important factors for CH₄ oxidation in municipal solid waste landfills.